Meet NeuroProof at the ISSCR 2018

Melbourne, June, 20-23

In collaboration with BrainXell, a Madison, Wisconsin US Company, NeuroProof GmbH presents brand new results on in vitro disease modeling using human motor neurons derived from patients who have either amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy (SMA).
Related neuronal activities were functionally phenotyped with NeuroProof's artificial intelligence analyses of multi-well microelectrode assay (MEA) data. Be invited to discuss our new disease models with the experts or get a free poster copy (contact us after the meeting).

Meet NeuroProof at the SfN

Washington D.C. 11-15.11.2017

NeuroProof presents its newest developments in functional phenotypic screening combined with multivariate and artificial intelligence analysis methods. We are seeking for collaboration partners and are glad to help to make your drug discovery projects a real success. Visit our posters to discuss new collaboration projects. Get an update on our service offers and models for neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Epilepsy, rare diseases and for safety pharmacology.

Get the chance to discuss our latest poster with our Project Manager Benjamin Bader.

Sunday, Nov. 12, 10.00-12.00 AM Functional biomarker of rare and familiar diseases: NPC1 knockout neuronal networks phenotyped with HTS microelectrode arrays and artificial intelligence machine learning methods (!/4376/presentation/21269) and

Mon, Nov. 13, 2017, 1:00 PM - 5:00 PM at the Poster Section 387.21 Identification of measurable phenotypes relevant to Alzheimer’s disease using human iPSC-derived neurons.!/4376/presentation/11119

NeuroProof at the ISSCR 2017

Boston, USA. June, 13-17

At the ISSCR stem cell meeting in Boston, Neuroproof's project manager Benjamin Bader will present novel results on a genotype/phenotype/transcriptome correlation using human iPSC neurons carrying Alzheimer's Disease-specific genetic variations which were functionally phenotyped with NeuroProof's artificial intelligence analyses of multi-well MEA data. Whole genome transcriptome data delivers further insights into the reasons for he functional phenotypes.

Poster number T-1136
Time: presenter time Thursday June, 15 at 7-8 PM.


AD/PD meeting in Vienna

March 28, 2017

Meet NeuroProof at the Annual Meeting for Alzheimers and Parkinson's Disease AD/PD 2017 in Vienna and discuss our newest functional assay for screening Alzheimer drugs on a human genetic APP-mutant cell culture model with Benjamin Bader at the poster on Thursday. We also present a new approach for comparing functional phenotypic effects of alpha-synuclein on mouse and human dopaminergic neurons. Visit the AD/PD website for the abstract:


Stem cells in drug discovery

March, 6-7th 2016, Cambridge

Meet NeuroProof Project Manager Benjamin  Bader at the Conference on Advances in Drug Discovery and discuss the latest NeuroProof assays for functional phenotypic CNS drug discovery using human stem cells.

Further information:

2nd Annual Conference on Neuroscience R&D Technologies

September, 29-30th 2016, London

Meet NeuroProof CEO Olaf Schröder at the 2nd Annual Conference on Neuroscience R&D Technologies conference and discuss the presentation and latest NeuroProof assays for functional phenotypic CNS drug discovery.

Further information:

NeuroProof at Axiogenesis Meeting in Cologne

September 7-9th 2016

NeuroProof project manager Dr. Benjamin Bader presented the latest results on functional phenotypic modeling of neuro-degenerative diseases using human iPSC-derived neurons and their comparison to well-known primary cell cultures growing on micro-electrode arrays. The topics presented include effects of alpha-synuclein and botulinum toxin on hIPSC derived neuronal networks.

MEA meeting 2016

Reutlingen, June 28th - July 1st

ISSCR stem cell meeting

San Francisco, 22-26.6.2016

If you are attending the ISSCR meeting in San Francisco, come visit our two NeuroProof contributions: 1) The poster by Nagel et al. about functional evaluation of Axol's patient-derived iPSC neurons carrying a presinilin-1 mutation presented by Naomi Wessel-Carpenter and 2) the poster by Bader et al. about multi-parametrically characterizing the functional in vitro phenotype of Axiogensis' different "4U" neuron series with data on seizurogenic compounds and on our novel phenotypic readout used for phenotypic in vitro disease modeling (here Parkinson) which is presented by Elena Kfoury.

World Preclinical Congress

Boston, 14-17.6.2016

NeuroProof and Axiogenesis present a poster about " Monitoring and adapting the functional phenotypic of developing human iPSC-derived neuronal networks using multi-variate analysis of MEA data". Visit out poster and discuss the latest developments in multi-parametric data analysis for phenotypic screening of human iPSC-derived neurons.