2015

Posters

  • A. Pielka, C. Ehnert, K. Jügelt, G. Rascher-Eggstein, O. H.-U. Schröder, A. Gramowski-Voss, B.M. Bader. Functional and phenotypic in vitro modeling of Parkinson’s disease and seizurogenic effects using human iPSC-derived neurons grown on micro electrode arrays (MEAs). Poster INGESTEM international congress, Paris, Nov. 19-20.

  • A. Gramowski-Voss, A.-M. Pielka, C. Ehnert, K. Jügelt, O. H.-U. Schroeder, B. M. Bader. Prediction of drug-induced seizure-liability in human iPSC-derived neuronal networks compared to primary mouse networks - functional, phenotypic In vitro assessment using micro-electrode arrays. Program No. 497.05. Neuroscience 2015 Abstracts. Chicago: Society for Neuroscience, 2015. Online.

  • A.-M. Pielka, A. Voss, C. Ehnert, K. Jügelt, O. H.-U. Schroeder, B. M. Bader. Increasing functional complexity and maturity of human iPSC-derived neuronal networks In vitro by glia co-culture and mixing different neuronal populations. Program No. 760.04. Neuroscience 2015 Abstracts. Chicago: Society for Neuroscience, 2015. Online.

  • B. M. Bader, A.-M. Pielka, C. Ehnert, K. Jügelt, A. Gramowski-Voss, O. H.-U. Schroeder. A functional phenotypic screening In vitro assay for novel Parkinson’s drugs - comparing effects of human iPSC-derived dopaminergic neuronal networks and primary mouse midbrain cultures. Program No. 53.24. Neuroscience 2015 Abstracts. Chicago: Society for Neuroscience, 2015. Online.

  • B. M. Bader, C. Kuang, C. Ehnert, K. Jügelt, A. Gramowski-Voss, Y. Xiao, R. McMahon, O. H.-U. Schroeder, D. Hondmann Functional Maturation of neuronal networks In vitro is accelerated by combination of bioactive whey protein, natural bovine complex lipids and DHA. Program No. 117.20. Neuroscience 2015 Abstracts. Chicago: Society for Neuroscience, 2015. Online.

  • C. Ehnert, A. Gramowki-Voss, B. M. Bader, O. H.-U. Schroeder An In vitro epileptogenesis mouse model for anticonvulsant drug screening. Program No. 497.04. Neuroscience 2015 Abstracts. Chicago: Society for Neuroscience, 2015. Online.

  • B. M. Bader, A. Pielka, C. Ehnert, K. Jügelt, A. Gramowski-Voss, D.G. Weiss, O. H.-U. Schröder. A novel functional in vitro phenotypic screening assay for detecting anti-Parkinson drugs using neuronal networks derived from dopaminergic human iPSCs. DGFZ2015, 25th Annual Conference of the German Society for Cytometry. Berlin, October 7-9th 2015.

  • B. Bader, A. Pielka, A. Voss, O. Schroeder. Human ipsc-derived neuronal networks growing on micro-electrode arrays used in novel phenotypic functional in vitro screening assays for Parkinson's and Alzheimer's drugs. 12th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders (AD/PD 2015). Abstract 360, online.

  • ESPGHAN 2015 in Amsterdam, may 6-9th 2015. Bader et al. "Combination of DHA with bioctive whey protein, natural bovine complex lipids accelerates functional maturation of neuronal networks in vitro" (PO-N-0365, Abstract online in Abstract book)

  • Co-poster presentation at SOT2015 meeting in San Diego, march 22-26th. Kettenhofen et al., Head of Lab, Axiogenesis: human iPSC-Derived Neurons: A Suitable Model For Functional and Toxicological Assays.

  • E. Dragicevic, N. Becker, S. Stölzle-Feix, U. Thomas, K. Juhasz, L. Doerr, M. Rapedius, A. Nicolini, D. Millard, Stacie Chvatal, B. Bader M. Beckler, M. George, A. Brüggemann, N. Fertig. Complementary automated patch clamp, extracellular field potential and impedance recordings of iPSCs: drug and safety screening tool box for the future. SCDD 2015 (download poster).

  • B. Bader, A. Pielka, K. Jügelt, C. Ehnert, A. Voss, O. Schroeder. Functional phenotypic screening for novel parkinson's drugs using human ipsc-derived dopaminergic neurons grown on micro-electrode arrays. ISSCR 2015 (download poster).

Talks

  • DGfZ2015, Berlin, Oral presentation at the 25th Annual Conference of the German Society for Cytometry. October 7-9th 2015. Prof. em. D. G. Weiss, co-founder NeuroProof: "A novel functional in vitro phenotypic screening assay for detecting anti-Parkinson drugs using neuronal networks derived from dopaminergic human iPSCs"

  • Axiogenesis user group meeting, Cologne, 15-17.04.2015; B. Bader, Project Manager, NeuroProof. FUNCTIONAL PHENOTYPIC SCREENING FOR NOVEL PARKINSON'S DRUGS USING HUMAN IPSC-DERIVED DOPAMINERGIC NEURONS GROWN ON MICRO-ELECTRODE ARRAYS

  • DDI 2015 Conference: Cell Based Assays, Phenotypic Screening and Pioneering Technologies:  March 17-18th, Berlin. O. H.-U. Schroeder, CEO, NeuroProof: "Phenotypic Screening in CNS Drug Discovery with Electrophysiological Recordings from Micro Electrode Arrays"

  • Axiogenesis workshop, Cologne, Nov. 26th 2015; B. Bader, Project Manager, NeuroProof. Functional and phenotypic in vitro disease modeling using human iPSC-derived neurons grown on Micro-electetrode arrays (MEAs)

  • MnM Conference, Barcelona, Dec. 3rd 2015, O. Schröder, CEO, NeuroProof. Functional phenotypic screening in vitro using human iPSC-derived neuronal networks grown on micro electrode arrays