Phenotypic Screening

The architecture of neuronal information processing is organized in three levels: intracellular signaling, communication between cells, and network communication. To understand each of these levels measurements of electrophysiological characteristics are necessary. Compound-induced activity profiles recorded with microelectrode arrays (MEA-neurochipstl_files/media/img/picture-icon.png) are sensitive and selective as well as robust and stable, allowing a precise pharmacological "phenotypic fingerprinting" to assess their therapeutic potential.

Using this multi-parametric information we study a wide range of phenomena within network activity patterns, e.g., inhibition, enhancement, regularity, synchronicity, or connectivity.

Read more about our proprietary data analysis and comparison to our database of functional “fingerprints” here.



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